Why is it important to separate Levothyroxine from other medications?

Separating Levothyroxine from other medications is crucial to ensure optimal absorption. Levothyroxine is a synthetic form of the thyroid hormone used to treat hypothyroidism. Its absorption in the gastrointestinal tract can be significantly affected by the presence of other substances, including certain medications, food, and supplements, especially those containing calcium, iron, or magnesium.

When taken alongside other medications, these substances can bind to Levothyroxine and hinder its absorption, which can lead to inadequate hormone levels in the body. This may result in suboptimal treatment outcomes for patients with thyroid disorders. To achieve therapeutic effectiveness, it is recommended to take Levothyroxine on an empty stomach, typically 30 to 60 minutes before breakfast or any other medications, to maximize its absorption and effectiveness.