Which supplement is noted for having a risk of hepatotoxicity?

Kava is well-documented for its potential risk of hepatotoxicity, which refers to liver damage. This risk has been highlighted through various studies and regulatory warnings. Kava is derived from the root of the kava plant, which is traditionally used in certain cultures for its relaxing and psychoactive properties. However, cases of liver toxicity, including hepatitis and liver failure, have been reported in individuals using kava supplements. This has led to some countries imposing bans or restrictions on kava products.

In contrast, valerian root, St. John's Wort, and chamomile are generally considered to have a lower risk for liver damage. While these supplements can have various side effects and interactions, there is less evidence to support a strong association with hepatotoxicity like that seen with kava. Understanding the potential adverse effects of various supplements, especially concerning liver health, is crucial for safe usage and avoidance of serious health risks.