Which side effect is commonly associated with Vinorelbine?

Vinorelbine, a chemotherapeutic agent used primarily in the treatment of non-small cell lung cancer and breast cancer, commonly causes alopecia as a side effect. This is due to its mechanism of action, which involves interfering with microtubule formation during cell division. Hair follicles, being some of the most rapidly dividing cells in the body, are affected by this disruption, leading to hair loss.

Patients receiving Vinorelbine may experience varying degrees of hair thinning or complete hair loss, depending on the dosage and individual susceptibility. While other side effects may occur with Vinorelbine, such as nausea due to its potential gastrointestinal impact or other effects like fatigue or nerve-related issues, alopecia stands out as a notable and widely recognized adverse effect associated with this specific drug.

This understanding is critical for both patient education and management of expectations during treatment, as hair loss can significantly impact a patient's quality of life.