Which pathogen is NOT typically associated with endocarditis?

Endocarditis is an infection of the inner lining of the heart chambers and valves, which can be caused by a variety of pathogens. The organisms most commonly associated with endocarditis are usually bacteria that can be divided into two main categories: those that are commonly found in the oral cavity and skin flora.

Streptococcus, Enterococcus, and Staphylococcus are all well-documented causes of endocarditis. For instance, Streptococcus viridans, which is part of the normal flora of the mouth, is a frequent cause, particularly after dental procedures. Enterococcus is typically involved in healthcare-associated infections, while Staphylococcus aureus is known for its virulence and is a common cause of acute endocarditis.

In contrast, Neisseria species are not commonly associated with endocarditis. While Neisseria gonorrhoeae can cause systemic infections and lead to endocarditis in rare cases, it is not a primary causative agent, nor is it typically found in the context of more common endocarditis pathogens. Therefore, the option relating to Neisseria is accurately identified as not typically associated with endocarditis, making it the correct choice.