Which of the following medications cannot be broken due to its formulation?

Felodipine is formulated as an extended-release medication, which means its design allows for a slow and consistent release of the active ingredient into the bloodstream over a prolonged period. Breaking or altering the tablet can disrupt this carefully controlled release mechanism, potentially leading to an immediate release of a large dose of the drug instead of the intended gradual release. This could increase the risk of side effects and lead to suboptimal therapeutic outcomes.

In contrast, the other medications listed have different formulations that allow them to be broken, crushed, or modified without significantly affecting their intended action. Understanding the implications of altering the formulation of a medication is critical in practice, particularly for drugs with extended-release properties like Felodipine. This knowledge helps ensure that medications are taken safely and effectively, maintaining therapeutic efficacy while minimizing risks.