Which of the following is a side effect associated with Thrombolytics?

Thrombolytics, often used to dissolve blood clots in conditions like myocardial infarction or stroke, have several significant side effects, with bleeding being one of the most serious. The use of thrombolytics increases the risk of hemorrhage due to their mechanism of action, which involves breaking down fibrin in blood clots. This can lead to both external and internal bleeding complications. Hypotension may also occur as a side effect, which can result from blood volume changes or bleeding leading to lower blood pressure.

While gastrointestinal upset, hypertension, and headache can occur for various reasons during treatment, they are not the primary or most serious side effects directly linked to thrombolytic therapy. The risk of bleeding and associated hypotension is a prominent concern that healthcare providers monitor closely in patients receiving these medications. This is why the answer indicating bleeding and hypotension is the most accurate choice regarding the side effects associated with thrombolytics.