Which of the following is a third-generation cephalosporin that can treat Neisseria gonorrhoeae?

Cefixime is recognized as a third-generation cephalosporin that is specifically effective against Neisseria gonorrhoeae, the bacterium responsible for gonorrhea. Third-generation cephalosporins are generally known for their enhanced activity against Gram-negative bacteria while maintaining some efficacy against Gram-positive organisms. Cefixime stands out due to its pharmacokinetic properties and ability to penetrate the bacterial cell wall, allowing it to effectively inhibit the growth of Neisseria gonorrhoeae.

Cefdinir and Cefpodoxime are also third-generation cephalosporins, but they are not typically the first-line treatment options for gonorrhea due to their bacterial spectrum. Meanwhile, Cefepime is a fourth-generation cephalosporin and, while it possesses a broader spectrum of activity, it is not primarily indicated for the treatment of gonorrhea. Thus, the choice of Cefixime aligns with clinical guidelines for managing infections caused by Neisseria gonorrhoeae.