Which of the following is a known side effect of Vancomycin?

Vancomycin is an antibiotic commonly used to treat serious gram-positive infections, particularly those caused by methicillin-resistant Staphylococcus aureus (MRSA). One of the well-documented side effects of Vancomycin is nephrotoxicity, which refers to potential damage to the kidneys. This risk is particularly pronounced in patients who are receiving high doses or those who have pre-existing renal impairment, dehydration, or who are also taking other nephrotoxic medications.

Monitoring kidney function is crucial when patients are on Vancomycin therapy. Elevated serum creatinine levels may indicate renal dysfunction, and clinicians often track these values to ensure safe dosing. If nephrotoxicity occurs, the antibiotic may need to be adjusted or discontinued, and supportive measures may be implemented.

The other options, while they can be significant with other medications, are not typically associated with Vancomycin. Cardiotoxicity, hepatotoxicity, and dermatotoxicity are not prominent risks with this particular antibiotic. Thus, nephrotoxicity stands out as a critical concern with Vancomycin treatment, reinforcing the need for careful patient monitoring during therapy.