Which of the following is a characteristic of Aztreonam (Azactam)?

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Aztreonam, marketed under the name Azactam, is a monobactam antibiotic that has a specific target profile, making it effective primarily against gram-negative bacteria. Its unique characteristic lies in its structure, which allows it to inhibit bacterial cell wall synthesis, a feature shared with other beta-lactam antibiotics. However, it is noteworthy that Aztreonam has minimal activity against gram-positive organisms and is not effective against anaerobes, further emphasizing its narrow spectrum of activity.

Therefore, the recognition that it targets gram negatives only accurately captures the essence of Aztreonam’s antibacterial action, making it the correct choice. This focus on gram-negative bacteria, including strains resistant to other antibiotics, makes Aztreonam a valuable therapeutic option in certain clinical scenarios, especially for patients with allergies to penicillin.

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