Which of the following is required for the storage of Toposar (etoposide)?

Etoposide, marketed as Toposar, requires refrigeration for optimal storage. The proper storage conditions are crucial in maintaining the drug's efficacy and stability. When stored at room temperature, certain medications can degrade more rapidly, leading to decreased effectiveness. Refrigeration helps to slow down these processes, ensuring the medication remains potent during its shelf life.

Additionally, while etoposide does need to be stored properly to ensure its effectiveness, it does not specifically require protection from light, which is commonly associated with other medications that degrade when exposed to light. This distinguishes etoposide's storage needs from those of other drugs that must be kept in dark environments.

Using refrigeration as a method of storage aligns with best practices for many chemotherapeutic agents, highlighting the importance of following specific guidelines in pharmaceutical handling to ensure patient safety and treatment effectiveness.