Which laboratory tests should be checked before administering Cannabidiol (Epidiolex)?

Before administering Cannabidiol (Epidiolex), it is important to check AST (aspartate aminotransferase) and ALT (alanine aminotransferase) levels as these enzymes are indicators of liver function. Cannabidiol is metabolized in the liver, and it can potentially cause elevation in liver enzymes. Monitoring AST and ALT levels helps assess the liver's health and function, allowing healthcare providers to ensure that the drug is not causing hepatotoxicity.

While it is essential to monitor other laboratory tests depending on the patient's condition, AST and ALT levels are specifically relevant to the administration of Cannabidiol. Checking these levels ensures that any liver-related issues are identified before starting treatment, thus mitigating potential complications. This approach underscores the importance of vigilant monitoring in patients undergoing treatment with substances that can affect liver function.