Which insulin has the shortest duration of action?

The insulin with the shortest duration of action among the options listed is Novolog. Novolog is a rapid-acting insulin, which means it starts working quickly—typically within 15 minutes after injection—and its effects can last for about 3 to 5 hours. This quick onset and short duration make it particularly suitable for managing blood sugar levels around meal times.

In contrast, the other insulins listed operate over longer durations. For example, Novolin N and Humulin N are both intermediate-acting insulins, with a duration of action ranging from 10 to 16 hours. Humulin R, being a short-acting insulin, has a duration of action of about 5 to 8 hours, longer than that of Novolog.

Understanding the different classifications and durations of various types of insulin is crucial for effective diabetes management, particularly in timing insulin administration concerning meals and blood sugar monitoring.