Which drug is indicated for the treatment of cytomegalovirus and may cause renal toxicity?

Cidofovir is a potent antiviral medication specifically indicated for the treatment of cytomegalovirus (CMV) infections, particularly in immunocompromised patients such as those with HIV/AIDS or those undergoing organ transplantation. One of the significant side effects associated with cidofovir is renal toxicity, which can lead to nephrotoxic effects. This risk is particularly important to monitor, as it necessitates adequate hydration and the possible use of probenecid to mitigate the nephrotoxic effects before and after administration.

The other antiviral medications listed may be used in the context of CMV infection; however, they do not share the same prominent risk for renal toxicity as cidofovir does. Thus, cidofovir is uniquely recognized for both its therapeutic use against CMV and its potential adverse effect on renal function.