Which drug combination is found in Biktarvy?

Biktarvy is a fixed-dose combination medication that is specifically used for the treatment of HIV-1 infection. The correct combination found in Biktarvy includes bictegravir, emtricitabine, and tenofovir alafenamide (TAF). Bictegravir is an integrase strand transfer inhibitor, which works by inhibiting the HIV integrase enzyme, thus preventing the viral DNA from integrating into the host's genome. Emtricitabine is a nucleoside reverse transcriptase inhibitor (NRTI) that blocks reverse transcription of HIV RNA into DNA. TAF is another NRTI that helps to reduce the viral load by inhibiting HIV replication.

This combination is particularly effective because it brings together the different mechanisms of action of each drug to better control the virus, reduce the chance of developing resistance, and minimize the side effects due to lower dosing of TAF compared to its predecessor, tenofovir disoproxil fumarate (TDF).

Understanding the correct composition is essential, especially since other combinations listed include different drugs or combinations that are not contained in Biktarvy, illustrating the importance of knowing drug classifications and their roles in HIV therapy.