Which benzodiazepine is used off-label for chemotherapy-associated nausea and vomiting?

Lorazepam is commonly used off-label for chemotherapy-associated nausea and vomiting due to its anxiolytic and sedative properties. It helps to reduce the anxiety that some patients experience prior to chemotherapy and can provide a calming effect, which may indirectly alleviate nausea and vomiting.

Furthermore, lorazepam has a longer duration of action compared to other benzodiazepines, making it suitable for managing symptoms over the course of chemotherapy treatments. Its specific pharmacological profile allows it to play a role in supportive care for patients undergoing cancer treatment, particularly in circumstances where other anti-nausea medications are ineffective or not well tolerated. This makes lorazepam a valuable option in the management of such symptoms in the oncology setting.