Which ACE inhibitor must be taken on an empty stomach?

Enalapril is the specific ACE inhibitor that must be taken on an empty stomach to ensure optimal absorption and effectiveness. When taken with food, the absorption of enalapril can be significantly reduced, which may diminish its therapeutic benefits.

For effective management of conditions like hypertension and heart failure, maintaining consistent drug levels in the bloodstream is crucial, and taking enalapril as directed (on an empty stomach) helps achieve that. The other ACE inhibitors listed can generally be taken with or without food, which allows for greater flexibility in their administration. This distinction is important for healthcare providers to communicate to patients, ensuring they receive the full benefit of their medication regimen.