What treatment is commonly used in managing acute exacerbations in asthma aside from SABA and steroids?

Magnesium sulfate IV is a treatment commonly used in managing acute exacerbations of asthma due to its bronchial smooth muscle relaxation properties. When administered intravenously, magnesium sulfate can help reduce bronchospasm and improve airflow in patients experiencing severe asthma attacks. This is particularly helpful in cases where traditional treatments, such as short-acting beta agonists (SABAs) and systemic corticosteroids, may not be sufficient to relieve symptoms.

The use of magnesium sulfate is generally reserved for more severe cases or those that do not respond adequately to first-line treatments. The drug works by interfering with calcium influx into cells, leading to muscle relaxation in the airways, which can significantly alleviate respiratory distress.

Other options like antivirals, antihistamines, and long-acting beta agonists are either not effective for acute exacerbations or are used in different contexts. Antivirals target viral infections rather than bronchospasm; antihistamines primarily address allergic reactions and are not indicated for acute asthma symptoms; and long-acting beta agonists are meant for long-term control, not for immediate relief during acute exacerbations.