What should Primaxin (Imipenem/Cilastatin) be made in for administration?

Primaxin, which is a combination of imipenem and cilastatin, is typically reconstituted in normal saline for administration. Normal saline is an isotonic solution that is commonly used in intravenous therapy because it closely matches the body's electrolyte balance and helps to ensure that the medication is adequately dissolved and delivered into the bloodstream without causing cellular dehydration or other complications.

Using normal saline provides a safe and effective medium for administering the medication, allowing for proper hydration and support of the medications' effectiveness within the body. Other solutions, such as sterile water, dextrose, or lactated Ringer's, may not provide the same isotonic environment or could potentially alter the way Primaxin behaves in the body, leading to less effective treatment or complications.