What should be done regarding LFTs when starting statin therapy?

When initiating statin therapy, checking liver function tests (LFTs) only at baseline is the recommended approach. This means that patients should have their LFTs assessed prior to starting the medication to ensure that there are no pre-existing liver conditions that could be exacerbated by statin use.

Statins can occasionally raise liver enzymes, but routine monitoring of LFTs after starting treatment is typically not necessary for most patients. This recommendation is based on clinical guidelines that suggest that the risk of serious liver damage associated with statins is low and that most patients do not experience significant liver function issues while on these medications. Therefore, unless the patient has symptoms suggestive of liver dysfunction or there are concerning clinical factors that arise during treatment, further routine testing after the initiation of therapy is generally unnecessary.