What should be done if a rash develops while taking Lamotrigine?

If a rash develops while taking Lamotrigine, the immediate and appropriate action is to stop the medication. Lamotrigine is known to potentially cause serious skin reactions, including Stevens-Johnson syndrome (SJS) and toxic epidermal necrolysis (TEN), which can be life-threatening. The risk of these severe reactions is higher with initial dosing or when the dosage is increased too quickly.

Recognizing the potential severity of rashes associated with this medication is crucial, and stopping it immediately helps mitigate the risk of progression to something more serious. Monitoring the rash is not advisable, as waiting could allow for further complications. Reducing the dose or attempting alternative interventions like skin tests do not address the urgent need to prevent a possibly severe outcome. Consulting a physician is important, but the priority is to discontinue Lamotrigine to ensure patient safety.