What process is used to reduce particle size when making a suspension?

The process of levigation is specifically used to reduce particle size when making a suspension. This technique involves the careful grinding of solid particles in a liquid, often using a mortar and pestle or a similar apparatus, to create a finer, more homogenous mixture. Levigation is particularly important in pharmaceutical formulations, as smaller particle sizes can enhance the stability of the suspension, improve the homogeneity, and increase the bioavailability of the drug.

In contrast, mixing generally refers to combining two or more substances without addressing their particle sizes. Adamantization is not a recognized term in this context; it may refer to something unrelated to particle size reduction. Dilution involves decreasing the concentration of a solution but does not entail any reduction in particle size. Thus, levigation is the correct process for achieving the desired fine particle size in a suspension.