What potential side effect is associated with Singulair (montelukast)?

Montelukast, commonly known by the brand name Singulair, is a medication primarily used to manage asthma and relieve symptoms of seasonal allergies. One notable potential side effect associated with its use is mood and behavior changes. These changes can include feelings of agitation, irritability, anxiety, depression, and in some cases, suicidal thoughts.

The mechanism by which montelukast may influence mood and behavior is not completely understood, but it is hypothesized to relate to its action on leukotriene receptors, which play a role in inflammatory processes in the brain. Hence, this side effect stands out as particularly significant and is highlighted in product labeling, prompting healthcare providers to monitor patients closely, especially in children and adolescents who may be more susceptible.

Other listed options, such as weight gain, headaches, and increased heart rate, may sometimes occur with various medications, but they are not prominently linked to montelukast in the same way mood and behavior changes are. Monitoring for psychological effects is crucial as it impacts the patient’s overall well-being and requires careful management.