What medication is indicated for early form diarrhea caused by Irinotecan?

The correct medication indicated for early form diarrhea caused by Irinotecan is Loperamide.

Irinotecan, a chemotherapy agent, can cause diarrhea as a side effect, which can occur acutely or later on following administration. The acute form of diarrhea is typically characterized by the onset of diarrhea within the first 24 hours after administration. Loperamide, an opioid, works by slowing down gut movement and increasing the time it takes for the contents of the intestines to pass, thereby reducing the frequency of bowel movements and alleviating diarrhea.

Atropine is not used for managing diarrhea; in fact, it can lead to constipation as a side effect. Diphenoxylate, another antidiarrheal, is similar but normally more indicated for chronic forms of diarrhea rather than the acute form associated with Irinotecan. Metoclopramide, primarily indicated for nausea and vomiting, would not be appropriate in this context either, as it is not effective for treating diarrhea. Therefore, Loperamide is the preferred choice when addressing the acute diarrhea caused by Irinotecan.