What is the treatment regimen for neurosyphilis?

The appropriate treatment regimen for neurosyphilis is often administered through intravenous penicillin G due to the need for adequate penetration of the central nervous system (CNS). The regimen consisting of 3 to 4 million units of penicillin G given IV every 4 hours for a duration of 10 to 14 days is effective in treating the infection by ensuring high drug levels are maintained in the bloodstream and CNS, which is critical given the potential severity of neurosyphilis and its complications.

This dosing schedule allows for a continuous therapeutic effect, which is essential because neurosyphilis can lead to significant neurological damage if not treated effectively. The specified dose and frequency are based on guidelines that emphasize the need for aggressive therapy in cases that affect the central nervous system to adequately clear the infection.

Other options such as oral tetracycline or intramuscular formulations would not provide the necessary CNS penetration and therapeutic levels required for effectively resolving neurosyphilis, which is why they are not suitable treatments for this specific condition.