What is the therapeutic range of digoxin for heart failure?

The therapeutic range of digoxin for heart failure is indeed between 0.5 and 0.8 ng/mL. This range is crucial because digoxin has a narrow therapeutic index, meaning that the difference between an effective dose and a toxic dose is small. Within this range, digoxin can help improve heart function and provide symptomatic relief for patients with heart failure by enhancing myocardial contractility and controlling heart rate.

Maintaining digoxin levels within this therapeutic range minimizes the risk of toxicity while ensuring therapeutic efficacy. Digoxin levels above this range can lead to adverse reactions, such as gastrointestinal disturbances, confusion, and even life-threatening cardiac arrhythmias. Therefore, monitoring and keeping digoxin levels within 0.5-0.8 ng/mL is essential for optimal treatment outcomes in heart failure.