What is the route of administration for Regitine (Phentolamine) in hypertensive crisis?

Regitine (Phentolamine) is administered intravenously (IV) or intramuscularly (IM) during a hypertensive crisis because this method allows for rapid absorption and onset of action, which is critical in emergency situations. In hypertensive crises, blood pressure must be lowered quickly to prevent potential complications, such as stroke or heart attack. The IV route is particularly favored as it provides precise control over the medication's effects and allows for immediate adjustments to dosing based on the patient's response.

Oral administration would not be suitable for a hypertensive crisis due to the delayed onset of action, which could prolong the situation and increase the risk of severe outcomes. Transdermal and inhalation routes do not provide the rapid response needed in an emergency setting, making them impractical for immediate intervention required for managing acute hypertension. Thus, the choice of IV/IM administration is essential for effective and prompt management in these critical situations.