What is the primary use of Zoloft (sertraline)?

Zoloft, known generically as sertraline, is primarily used to treat Major Depressive Disorder. It is classified as a selective serotonin reuptake inhibitor (SSRI) and is effective for a range of mood and anxiety disorders. While it is also approved for use in conditions such as Generalized Anxiety Disorder, Post-Traumatic Stress Disorder, and Panic Disorder, its primary and most common indication is for Major Depressive Disorder.

Sertraline works by increasing the levels of serotonin in the brain, which can help improve mood and alleviate symptoms of depression. It is widely prescribed and has a robust track record in clinical studies specifically aimed at treating depression as a primary indication. Consequently, recognizing Major Depressive Disorder as the correct answer highlights its central role in Zoloft's therapeutic profile.