What is the primary use of Hexalen (altretamine)?

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Hexalen, also known as altretamine, is primarily used in the treatment of ovarian cancer. It is an alkylating agent that, after activation in the body, works by interfering with the DNA of cancer cells, thus preventing them from dividing and growing. In the context of ovarian cancer, it is particularly utilized for patients who have previously received chemotherapy and may be used in combination with other treatments to improve outcomes.

The choice of this answer is supported by clinical indications of altretamine, which is specifically approved for use in cases of persistent or recurrent ovarian cancer. This positions it firmly within the domain of gynecological oncology. While altretamine can have some off-label uses or may be studied in other cancer types, its primary and most established indication remains ovarian cancer.

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