What is the primary use of Savella (milnacipran)?

Savella (milnacipran) is primarily used for the treatment of fibromyalgia, a condition characterized by widespread musculoskeletal pain, fatigue, and tenderness in localized areas. Milnacipran is a serotonin-norepinephrine reuptake inhibitor (SNRI) that helps alleviate the symptoms associated with fibromyalgia by increasing the levels of neurotransmitters in the brain that are important for mood and pain regulation.

This usage is supported by clinical studies demonstrating its efficacy in reducing pain and improving overall function in patients with fibromyalgia. While other conditions like major depressive disorder, anxiety disorders, and chronic fatigue syndrome can involve overlapping symptoms, Savella's specific approval and clinical research focus on the management of fibromyalgia, making it the most appropriate and correct answer.