What is the primary treatment for pseudoparkinsonism associated with antipsychotic use?

The primary treatment for pseudoparkinsonism, which is often induced by the use of antipsychotic medications, typically involves the use of anticholinergic agents such as benztropine, trihexyphenidyl, or diphenhydramine (Benadryl). These medications help alleviate the symptoms associated with the disorder, such as tremors, rigidity, and bradykinesia, by restoring the balance of neurotransmitters in the brain, specifically counteracting the dopamine antagonism caused by antipsychotics.

Anticholinergic medications work by blocking the action of acetylcholine, which can help to reduce the extrapyramidal side effects that resemble Parkinson's disease. This treatment is often effective and is preferred due to its ability to specifically target the symptoms rather than simply stopping or altering the antipsychotic medication, which could lead to a relapse of the underlying psychiatric condition.

Other treatment options may not be as effective in addressing the specific symptoms of pseudoparkinsonism or could potentially worsen the patient's overall condition. For instance, increasing the dosage of the antipsychotic could lead to more severe side effects, while physical therapy might help with mobility issues but does not directly address the underlying pathophysi