What is the primary indication for Methazolamide (Neptazane)?

Methazolamide, marketed under the brand name Neptazane, is primarily indicated for its action as an oral carbonic anhydrase inhibitor. This class of medications works by inhibiting the enzyme carbonic anhydrase, which plays a crucial role in various physiological processes such as fluid balance, pH regulation, and bicarbonate production. The primary therapeutic use of methazolamide is in the treatment of conditions like glaucoma, where reducing intraocular pressure is essential.

By inhibiting carbonic anhydrase, methazolamide decreases the production of aqueous humor in the eye, thus lowering the pressure within the eye. This mechanism is distinct from the treatment of chronic pain, anxiety, or insulin resistance, which do not relate to the primary function of methazolamide. Therefore, option B correctly identifies the primary indication for this medication, aligning with its pharmacological action and clinical applications.