What is the maximum daily dose for Trintellix (Vortioxetine)?

Trintellix, or vortioxetine, is an antidepressant medication used to treat major depressive disorder. The maximum recommended daily dose for adults is 20 mg. This dosage has been established through clinical studies that evaluate both efficacy and safety, ensuring that higher doses do not offer significant additional benefits while increasing the risk of side effects.

For patients requiring a medication adjustment, the prescribing guidelines suggest starting doses at lower levels, typically 10 mg, which can be increased based on the clinical response and tolerability, there’s a clear upper limit to maintain patient safety and drug efficacy. The other dosages listed (10 mg, 15 mg, and 25 mg) do not represent the established maximum for effective treatment. Choosing 20 mg aligns with the latest guidelines and reflects standard practice.