What is the max daily dose of Fetzima (levomilnacipran) for treating major depressive disorder?

The maximum daily dose of Fetzima (levomilnacipran) for treating major depressive disorder is 120 mg. This dosage is part of the dosing guidelines aimed at ensuring efficacy while minimizing side effects. Levomilnacipran is a serotonin and norepinephrine reuptake inhibitor that requires careful dosage management because, at higher doses, it can provide improved therapeutic effects for patients who do not sufficiently respond to lower doses. Specifically, starting dose recommendations are lower, generally around 40 mg, after which the dosage can be titrated to reach the maximum daily limit of 120 mg, depending on individual patient response and tolerability. Understanding and adhering to this maximum dosing is essential in clinical practice to optimize treatment outcomes for patients with major depressive disorder.