What is the main route of administration for Paliperidone?

Paliperidone is primarily administered orally, which is the most common route for this medication. When taken orally, Paliperidone typically comes in the form of extended-release tablets, allowing for once-daily dosing. This method of administration makes it convenient for patients, as it does not require any specialized training or settings for use, unlike injectable forms.

While there are indeed other routes of administration for Paliperidone, such as intramuscular (IM) injection for the long-acting formulation, the question specifically asks for the main route, which is the oral form used for daily management of symptoms. Intravenous administration, while applicable in some healthcare settings for different medications, is not a standard route for Paliperidone. Similarly, sublingual routes are not utilized for this drug.

This distinction highlights the predominant use of the oral formulation as the mainstay for treating conditions such as schizophrenia and schizoaffective disorder.