What is the main purpose of the quadruple therapy for H. pylori?

The main purpose of quadruple therapy for H. pylori is to eliminate the bacteria. This treatment regimen typically includes a combination of two antibiotics, a proton pump inhibitor, and sometimes a bismuth compound. The antibiotics work collectively to target and kill the H. pylori bacteria, while the proton pump inhibitor reduces stomach acid, creating a more favorable environment for the antibiotics to work effectively. Successful elimination of H. pylori is crucial for treating associated conditions like peptic ulcers and reducing the risk of stomach cancer.

While reducing stomach acidity is part of the therapy through the use of proton pump inhibitors, the primary goal is the complete eradication of the bacteria itself. Therefore, quadruple therapy specifically aims at addressing the underlying infection rather than simply managing symptoms or conditions such as asthma or digestion.