What is the main concern for patients taking Tenofovir?

Tenofovir, an antiretroviral medication used primarily for the treatment of HIV and chronic hepatitis B, has been associated with specific side effects that clinicians monitor closely. The main concern for patients taking Tenofovir revolves around osteoporosis and renal impairment.

Tenofovir can lead to decreased bone mineral density, which raises the risk of osteoporosis, particularly in patients who may already have other risk factors for bone loss. This is crucial for healthcare providers to consider, especially in patients with a history of bone-related conditions or those who are older. Additionally, Tenofovir has been linked to renal toxicity, which can manifest as elevated creatinine levels and renal tubular dysfunction, leading to complications if not managed properly.

While gastrointestinal distress, weight loss, and neuropathy can be side effects of various medications, they are not primarily associated with Tenofovir. The specific risk to bone health and kidneys makes osteoporosis and renal impairment the main concerns that should be highlighted when monitoring patients receiving this medication.