What is the initial dosing strategy for Tiagabine (Gabitril)?

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Tiagabine, marketed as Gabitril, is typically initiated at a dose of 4 mg daily for adults. This initial dosing strategy is designed to provide a balance between efficacy and tolerability, allowing the patient's body to gradually adjust to the medication. Starting at the 4 mg level helps minimize the risk of side effects while assessing the patient's response to treatment.

While other doses such as 2 mg, 8 mg, or 12 mg are options that may be relevant in specific contexts or for different populations, they do not represent the standard starting point for most patients on Tiagabine. Beginning therapy with a dose of 4 mg daily ensures that the clinician can monitor for adverse effects closely and determine the most effective dose to achieve seizure control as therapy progresses.

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