What is the formula for the Cockcroft-Gault equation for men?

The Cockcroft-Gault equation is used to estimate renal function and is particularly helpful in determining the creatinine clearance rate. For men, the formula is structured to account for age and other factors that influence kidney function.

The correct formulation is expressed as follows: (140 - age) multiplied by weight in kilograms (KG), and then divided by the plasma creatinine level (plasma Cr) multiplied by 72. This structure incorporates age to recognize that kidney function typically declines with advancing age, while weight ensures that the calculation is appropriately scaled to the individual's body mass. The division by 72 is a normalization factor that adjusts the creatinine levels, which are an indicator of kidney performance.

The use of 72 as a factor helps fine-tune the calculation, reflecting the average creatinine clearance in the population and allowing for a more accurate assessment based on standard parameters for healthy kidney function. Thus, this equation gives a valuable estimate of how well the kidneys are functioning by measuring how efficiently they can clear creatinine from the bloodstream.