What is the expected rate of thrombosis after using a bare metal stent?

The expected rate of thrombosis after the deployment of a bare metal stent is notably focused within the first month. This is primarily due to the body’s response to the stent and the healing process that ensues. Bare metal stents can lead to thrombosis more readily during this early period as they require endothelialization, a process where the cells lining the blood vessels overlay the stent to mitigate the risk of clot formation.

During the first month, the stent poses a risk because it does not have a drug-eluting coating to help reduce the inflammatory response and promote healing, which is often seen with newer stent technologies. After this initial period, the risks of thrombosis typically decrease significantly as the endothelium begins to cover the stent surface.

While thrombosis can occur after this period, especially in patients who do not follow appropriate dual antiplatelet therapy or in those with other risk factors, the highest incidence is concentrated around that one-month mark. This understanding underscores the importance of monitoring and managing patients closely during this critical timeframe after stent placement.