What is the dosage of Eliquis (Apixaban) for stroke prophylaxis in nonvalvular atrial fibrillation?

For stroke prophylaxis in nonvalvular atrial fibrillation, the standard dosage of Eliquis (Apixaban) is 5 mg taken orally twice a day (BID). This dosing regimen has been established based on clinical trials demonstrating its efficacy in reducing the risk of stroke in patients with this condition. The 5 mg dose reflects an appropriate balance between effectiveness and safety in a broad patient population.

In some specific circumstances, such as when patients meet certain criteria (e.g., age, weight, or renal function), a reduced dose of 2.5 mg orally BID may also be considered. However, for the general dosing recommendation for stroke prevention in nonvalvular atrial fibrillation, the preferred dosage is clearly 5 mg BID. This ensures that patients receive an adequate anticoagulation effect to mitigate the risk of thromboembolic events associated with atrial fibrillation.