What is the composition of Stribild?

Stribild is a fixed-dose combination medication used in the treatment of HIV. The correct composition of Stribild is elvitegravir, cobicistat, emtricitabine, and tenofovir disoproxil fumarate (TDF).

Elvitegravir is an integrase inhibitor, which helps prevent the virus from integrating its genetic material into the host cell’s DNA, thereby inhibiting its replication. Cobicistat serves as a booster for elvitegravir, enhancing its effectiveness by inhibiting enzymes that would otherwise break down elvitegravir in the body. Emtricitabine is a nucleoside reverse transcriptase inhibitor, which works by interfering with the virus’s ability to replicate. Tenofovir disoproxil fumarate is another antiretroviral medication that also acts as a nucleoside reverse transcriptase inhibitor.

Understanding this combination is essential because the specific components work synergistically to provide comprehensive treatment by attacking the virus at various points in its lifecycle, thus helping in the management and control of HIV.