What is the bioavailability ratio of intravenous ciprofloxacin compared to its oral form?

The bioavailability ratio of intravenous ciprofloxacin compared to its oral form is indeed about 100%. This means that when ciprofloxacin is administered intravenously, the entire dose reaches systemic circulation without any loss, in contrast to oral administration where some fraction may be lost due to factors such as first-pass metabolism or incomplete absorption due to gastrointestinal factors.

The correct answer is that the bioavailability of intravenous ciprofloxacin is equal to that of its oral form, which is why the ratio is considered to be 100% of oral administration. In practical terms, this indicates that intravenous use of ciprofloxacin offers the same therapeutic effect as oral dosing, providing flexibility in treatment routes depending on the patient's needs.

The other options suggest that the intravenous form delivers only a fraction of the oral form's dose, which is not the case for ciprofloxacin. Understanding this pharmacokinetic principle is essential for ensuring optimal dosing and treatment efficacy in clinical practice.