What is the active ingredient in Hyzaar?

Hyzaar is a combination medication that includes two active ingredients: losartan and hydrochlorothiazide. The key active ingredient responsible for its primary therapeutic effect, especially regarding its role as an angiotensin II receptor blocker (ARB), is losartan. Losartan works by blocking the action of a substance in the body that causes blood vessels to constrict, which helps to lower blood pressure and improve blood flow.

In the context of this question, focusing on losartan as the active ingredient highlights its significance in hypertension management as well as potential benefits in protecting kidney function in certain populations, such as those with diabetes. Recognizing losartan as the active component in Hyzaar emphasizes its importance in cardiovascular pharmacotherapy.