What is spatulation primarily used for in powder preparation?

Spatulation is primarily used in powder preparation to combine powders without creating dust. This technique involves using a spatula or similar tool to mix powders carefully on a flat surface, which helps to achieve a uniform blend while minimizing the risk of airborne particles that can occur with more vigorous mixing methods. The gentle nature of spatulation allows for effective mixing while maintaining the integrity of the particulate components, making it especially useful in applications where preserving the original characteristics of the powders is essential, such as in pharmaceutical formulations.

The other options do not accurately represent the primary function of spatulation. Dissolving solids typically requires liquid solvents and is not directly related to the dry mixing of powders. Heating a mixture is a different process used for other purposes, such as synthesis or dissolution, and it is not associated with spatulation. Freezing compounds is an entirely different method used for preservation or modification and has no connection to the powder mixing technique of spatulation.