What is one of the notable side effects of Paclitaxel?

Fluid retention is considered one of the notable side effects of Paclitaxel, a chemotherapeutic agent commonly used in the treatment of various cancers, including breast and ovarian cancer. This side effect can occur due to the drug's impact on the capillaries and its potential to alter fluid homeostasis in the body. Fluid retention might manifest as peripheral edema, which is swelling due to the accumulation of fluid in tissues, and can affect a patient’s overall comfort and may require management strategies to alleviate symptoms.

Understanding fluid retention as a side effect is essential for healthcare professionals monitoring patients undergoing treatment with Paclitaxel, as it can influence treatment decisions and the patient's quality of life. Recognizing this can prompt additional assessments and interventions to manage any discomfort or complications arising from this side effect.

Other options listed may represent side effects found in various medications, but fluid retention is particularly associated with Paclitaxel, making it the correct choice.