What is an important consideration to monitor while a patient is on Zyban?

When a patient is prescribed Zyban (bupropion), it is crucial to monitor for seizure activity. This medication is known to have a dose-dependent risk of seizures, particularly in individuals who have a history of seizures, eating disorders, or are withdrawing from alcohol or sedatives. The mechanism behind this risk is thought to be associated with the lowering of the seizure threshold that occurs with bupropion, especially at higher doses.

It is essential to be vigilant about any signs of seizures or changes in neurological status, as they may necessitate immediate medical intervention. Monitoring for potential triggers, such as changes in dosage or co-administration of other medications that could lower seizure thresholds, is also a key part of patient management while on Zyban.

In contrast, while vision changes, skin rash, and respiratory issues are important health concerns, they are not as directly linked to the use of Zyban, making seizure activity the primary focus during treatment with this medication.