What is a well-known potential side effect of Trastuzumab?

Trastuzumab, a monoclonal antibody used primarily in the treatment of HER2-positive breast cancer, is associated with cardiotoxicity as a well-known potential side effect. This occurs due to its pharmacological action, which can impact the heart muscle, leading to issues such as decreased left ventricular ejection fraction and, in some cases, heart failure. Monitoring heart function is essential during treatment with Trastuzumab, especially in patients who may already have underlying heart conditions or are receiving concurrent chemotherapy that may also affect heart health.

While nephrotoxicity, hepatotoxicity, and neuropathy can be side effects of other cancer treatments, they are not commonly associated with Trastuzumab. Understanding the specific adverse effects of drugs is crucial for proper patient management and monitoring during therapy.