What is a significant risk associated with Tenofovir?

Tenofovir is an antiretroviral medication primarily used to treat HIV and hepatitis B. A significant risk associated with Tenofovir is renal impairment. The drug can cause dose-dependent nephrotoxicity, which may manifest as a decrease in renal function, increased creatinine levels, or even acute kidney injury. Monitoring renal function in patients on Tenofovir is crucial, particularly for those who may already have underlying renal issues.

While other options may relate to the side effects of different classes of medications, the specific association of Tenofovir with renal impairment is well-documented in clinical studies and drug safety profiles. Understanding this risk is essential for healthcare providers to ensure that patients are appropriately monitored and managed while receiving treatment with this medication.