What effect do ACE inhibitors generally have on blood pressure?

ACE inhibitors, or angiotensin-converting enzyme inhibitors, are primarily used to manage high blood pressure. They function by blocking the activity of the enzyme responsible for the conversion of angiotensin I to angiotensin II, a potent vasoconstrictor. By inhibiting this process, ACE inhibitors cause blood vessels to relax and widen, leading to a decrease in blood pressure. This reduction in vascular resistance means that the heart does not have to work as hard to pump blood throughout the body, which is particularly beneficial for individuals with hypertension.

While the other options suggest effects like stabilization, increase, or fluctuation, these do not accurately capture the primary action of ACE inhibitors, which is to promote a lowering of blood pressure levels consistently and effectively.