What are the active ingredients in Mavyret?

Mavyret contains the active ingredients glecaprevir and pibrentasvir, which work together to treat chronic hepatitis C. Glecaprevir is a protease inhibitor that disrupts the viral lifecycle, preventing the hepatitis C virus from replicating. Pibrentasvir, on the other hand, is an NS5A inhibitor, which interferes with the virus’s ability to assemble and release new viral particles. The combination of these two drugs allows for effective treatment across multiple genotypes of the hepatitis C virus.

Other options listed include combinations of different antiviral agents used to treat hepatitis, but they do not represent the active ingredients found in Mavyret. For example, ribavirin, while an antiviral medication, is not included in Mavyret's formulation. Similarly, paritaprevir and ombitasvir are part of other hepatitis C treatment regimens, but they are not present in Mavyret. Lastly, sofosbuvir and velpatasvir are also different combinations used for hepatitis treatment but do not pertain to Mavyret. The unique combination of glecaprevir and pibrentasvir is what distinguishes Mavyret as a treatment option for hepatitis C.